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    Did you mean Myofibroblast Differentiation?
    GlossaryMyofibroblast Differentiation

    process where fibroblasts transform into wound-healing myofibroblasts

    Myofibroblast differentiation is the process by which fibroblasts, a type of cell found in connective tissue, transform into myofibroblasts. These myofibroblasts play a crucial role in wound healing and tissue repair by contracting and producing extracellular matrix components, which help close wounds and restore tissue integrity. However, excessive myofibroblast activity can lead to fibrosis, a condition characterized by excessive tissue scarring.

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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Verteporfin

      chemical that might completely regrow follicles from hair transplant extractions

      learn Redensyl

      commercial product with a blend of mostly natural ingredients for hair regrowth

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

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      a synthetic cortisol used for anti-inflammatory effects

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      community Verteporfin and Microneedling

      in Treatments 6 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  743 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.