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Glossary Microarray Analysis

examines gene expression levels across thousands of genes simultaneously

Microarray Analysis, also known as Gene Chip Analysis or DNA Microarray Analysis, is a laboratory technique used to study the expression levels of many genes simultaneously. It involves placing thousands of DNA sequences on a small chip, then exposing it to a sample to see which genes are active or inactive. This method is particularly useful for understanding complex genetic conditions, such as alopecia, by identifying which genes are involved in the disease process.

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research DNA Microarray and Bioinformatic Analysis Reveals the Potential of Whale Oil in Enhancing Hair Growth in a C57BL/6 Mice Dorsal Skin Model

May 2024 in “Genes”

In this study, 20% whale oil applied to mice was observed to promote hair growth more effectively than a control or 3% minoxidil, showing increased hair follicles and thicker subcutaneous tissue.

research DNA Microarray and Bioinformatic Analysis Reveals the Potential of Whale Oil in Enhancing Hair Growth in a C57BL/6 Mice Model

April 2024

In this study using female mice, researchers observed that topical application of 20% whale oil was more effective in promoting hair growth compared to a standard 3% minoxidil solution, with additional findings suggesting reduced stress- and inflammation-related responses with whale oil.

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

47 citations , July 2004 in “Journal of Dermatological Science”

In this study, decreased expression of BMP2 and ephrin A3 and increased NT-4 gene expression were observed in dermal papilla cells from androgenic alopecia-affected skin, suggesting potential roles in hair growth regulation.

Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus Terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis

research Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis

5 citations , May 2022 in “Biomedicines”

This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.

research Differential Gene Expression Screening Between Black and Gray Hairs Using Subtractive Library and DNA Chip

January 2004 in “Linchuang pifuke zazhi”

This study identified specific genes that are more abundantly expressed in black hair than in gray hair, with black hair displaying higher expression of pigment-related proteins and gray hair showing increased expression of keratin-related genes.

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