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Glossary Cytokine Expression

process where cells produce proteins to regulate immune responses

Cytokine expression refers to the process by which cells produce and release cytokines, which are small proteins that act as messengers to regulate immune responses and inflammation. In the context of hair and alopecia, abnormal cytokine expression can lead to inflammation around hair follicles, potentially contributing to hair loss.

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Research

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Wasabi Leaf Extract Changes the Expression Levels of Cytokine Related Genes in Dermal Papilla Cells, Identified by the Whole Transcriptome

research Wasabi leaf extract changes the expression levels of cytokine related genes in dermal papilla cells, which identified by the whole transcriptome

May 2025

In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.

Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome

research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome

69 citations , September 2006 in “Human Reproduction”

This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.

research Effects of Lavender Oil on Hair Growth-Relevant Enzyme Activity and Cytokine Expression in C57BL/6 Mice

1 citations , March 2016 in “Journal of Investigative Cosmetology”

This study found that lavender oil increased hair growth-related enzyme activity and cytokine expression, indicating potential hair growth-promoting effects in C57BL/6 mice.

research The Effects of Rosemary Oil on the Activities of Enzyme and Expression of Cytokine Relevant to Hair Growth in C57BL/6 Mice

January 2010 in “Jounal of The Korean Society of cosmetology”

Rosemary oil may promote hair growth by enhancing enzyme activities and IGF-1 expression.

research Ultraviolet B irradiation increases the expression of inflammatory cytokines in cultured sebocytes

20 citations , December 2013 in “Journal of Dermatology”

This study found that UV-B exposure significantly increased the expression of inflammatory cytokines IL-1β and IL-8 in cultured sebocytes.

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Community Join

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community Anti-oxidants that reverse hairloss?

86 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community Someone please offer reassurance

in Minoxidil 3 upvotes 1 month ago

A 19-year-old male is experiencing hair shedding while using oral minoxidil, ketoconazole, dermastamping, and saw palmetto, and is considering switching to finasteride for better results. Users suggest that saw palmetto may not be effective and recommend finasteride instead, while also discussing other treatments like rosemary oil, peppermint oil, and pumpkin seed oil.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

121 upvotes 2 years ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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Learn

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learn Stem Cell Factor

learn Procyanidin

bioflavonoid found in plants with antioxidant and hair stimulating properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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