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GlossarySMAD4

protein involved in TGF-beta signaling, affecting cell growth and differentiation

SMAD4, also known as Mothers against decapentaplegic homolog 4, is a protein that plays a crucial role in the TGF-beta signaling pathway, which is involved in regulating cell growth, differentiation, and apoptosis. Mutations in the SMAD4 gene can lead to various medical conditions, including certain types of cancer and hereditary hemorrhagic telangiectasia.

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community Creatine's effect on Hair Loss and DHT

in Research/Science 100 upvotes 8 months ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community What's your option on complementary treatment

in Product 3 upvotes 5 months ago

The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

community Minox and fin since start of January 2020, also shaved my head twice since then to get full effects of the minoxidil and reach the whole scalp easier, that’s honestly a huge key

in Progress Pictures 235 upvotes 3 years ago

User experienced significant hair regrowth using Minoxidil and Finasteride since January 2020, with no side effects reported. Shaving head twice helped Minoxidil reach scalp more effectively.

community Progress – 24.03.21 – 29.06.22 Finasteride 1mg a day

in Progress Pictures 1075 upvotes 2 years ago

A user's progress with treating hair loss using 1mg finasteride per day, with reports of no noticeable side effects and positive results. Other users have shared their experiences with different treatments, such as Dutasteride and Minoxidil.

community 2.5 months topical minoxidil Progress

in Progress Pictures 434 upvotes 9 months ago

The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

in Finasteride/Dutasteride 37 upvotes 1 year ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community 4.5 months/ Fin+Niz+Keto+Vitamins+Derm+Cold Water only washes

in Progress Pictures 622 upvotes 3 years ago

User achieved hair regrowth in 4.5 months using Fin, Min, Nizoral, vitamins, dermarolling, and cold water washes. Cold water washes improved scalp health, but unsure if significant contributor to regrowth.

community 3 month progress on min + fin capsule

in Is this regrowth? 400 upvotes 1 month ago

The user experienced significant hair regrowth in three months using a capsule containing minoxidil and finasteride. They reported no major side effects and plan to continue the treatment until their late 20s.

community 30yo, Dut 0.5mg/day, min 5% once/day, biotin 1000mg 3times/week, derma once/week, anaphase+ 2times/week, nizoral 2 times/week

in Progress Pictures 215 upvotes 10 months ago

A 30-year-old uses Dutasteride, Minoxidil, biotin, dermarolling, Anaphase+ shampoo, and Nizoral for hair loss. Some commenters question the need for such extensive treatment given the minimal hair loss.

community Almost 2 months on fin / nizoral shampoo / microneedling 1x week

in Progress Pictures 390 upvotes 1 year ago

User shares progress after 2 months using finasteride, nizoral shampoo, and microneedling for hair loss. Comments discuss early treatment, results, and differing opinions on starting treatments.

community Goodbye my dudes

in Finasteride/Dutasteride 305 upvotes 4 years ago

A user decided to stop using finasteride due to side effects and chose to shave their head instead. They plan to use the money saved for a hair transplant towards a house downpayment, hoping for future advancements in hair cloning.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 367 upvotes 3 weeks ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Male pattern baldness, and mental health

in Finasteride/Dutasteride 330 upvotes 9 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community 14 Months on nuclear stack (0,5 DUT and 15mg oral Minox and no regrowth. Aga is impossible to beat

in Progress Pictures 11 months ago

The user has been on a hair loss treatment for 14 months using dutasteride and oral minoxidil without seeing regrowth and is considering adding more drugs due to the psychological impact of hair loss. However, replies suggest the user may not actually be experiencing noticeable hair loss.

community 6 Month Update: Finasteride 1mg + Minoxidil + Nizoral

in Progress Pictures 313 upvotes 1 year ago

With some minox This conversation is about a user, Jmilei, who has been using the "big three" hair loss treatments (Finasteride, Minoxidil, and Ketoconazole) for five years. After taking a two year break from treatment, they have recently restarted their regime and noticed results in the fourth month.

community Wanted to give another update with another month down using finasteride, minoxidil, and micro needling. Trying to give consistent progress updates.

in Progress Pictures 515 upvotes 3 years ago

User shares progress update on hair loss treatment using finasteride, minoxidil, and microneedling. Others congratulate and ask questions about treatment details, such as microneedling tool, needle size, and side effects.