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Did you mean Chemotherapy-Induced Alopecia?

Glossary Chemotherapy-Induced Alopecia

hair loss caused by chemotherapy treatments for cancer

Chemotherapy-Induced Alopecia (CIA) refers to hair loss that occurs as a side effect of chemotherapy treatments for cancer. Chemotherapy drugs target rapidly dividing cells, which include not only cancer cells but also hair follicle cells, leading to hair thinning or complete loss. This condition is usually temporary, with hair typically regrowing after the completion of treatment.

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Research

5 / 1000+ results

research Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia.

219 citations , July 1995 in “PubMed”

This study found that recombinant keratinocyte growth factor (rKGF) stimulated hair growth and provided a protective effect against alopecia in murine models, suggesting its role in hair follicle development and regeneration.

Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies

research Chemotherapy-Induced Alopecia

155 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

This review covers various strategies to manage chemotherapy-induced alopecia, highlighting that agents like AS101 and minoxidil can reduce its severity but not prevent it, with no new clinical results reported.

research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors

153 citations , January 2001 in “Science”

In a neonatal rat model, this study found that topical CDK2 inhibitors reduced chemotherapy-induced hair loss in 33 to 50% of the animals, suggesting a potential strategy for preventing alopecia in cancer patients.

research A randomized trial of minoxidil in chemotherapy-induced alopecia

127 citations , July 1996 in “Journal of The American Academy of Dermatology”

This study found that in women undergoing chemotherapy after breast surgery, topical minoxidil significantly shortened the duration of hair loss compared to a placebo without significant side effects.

research Efficacy of interventions for prevention of chemotherapy‐induced alopecia: A systematic review and meta‐analysis

110 citations , August 2014 in “International journal of cancer”

This study found that scalp cooling significantly reduced the risk of chemotherapy-induced alopecia in breast cancer patients, while topical minoxidil and other interventions did not show significant efficacy.

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Community Join

5 / 47 results

community Why Fin/Dut is always recommended. The top 10 reasons for hairloss in men.

2 upvotes 1 year ago

Hair loss in men is primarily caused by androgenetic alopecia, with treatments like finasteride and dutasteride often recommended. Other causes include stress, nutritional deficiencies, medications, and scalp infections.

community The perfect reverse reverse hair-loss nuclear stack for those who feel left out

in Satire 415 upvotes 1 year ago

A satirical discussion on intentionally inducing hair loss using harmful habits and substances like cigarettes, junk food, anabolic steroids, and stress. The conversation humorously suggests extreme measures like chemotherapy and hydrofluoric acid, while also mentioning the ineffectiveness of sulfates and pumpkin seed oil in hair loss prevention.

community Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?

7 upvotes 1 year ago

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

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