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5 / 38 resultslearn Spironolactone
powerful topical and oral anti-androgen used mostly by women
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Ketoconazole
antifungal with some anti-androgenic benefits, often used as a shampoo
Research
5 / 1000+ results![The Distribution of Estrogen Receptor β Is Distinct to That of Estrogen Receptor α and the Androgen Receptor in Human Skin and the Pilosebaceous Unit](/images/research/0a148d7b-3005-43be-95ce-2d04dfd58259/small/15395.jpg)
research The Distribution of Estrogen Receptor β Is Distinct to That of Estrogen Receptor α and the Androgen Receptor in Human Skin and the Pilosebaceous Unit
Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
research What does the research say about androgen use and cerebrovascular events?
Androgen use may increase the risk of stroke, but more research is needed.
![Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice](/images/research/ebacac5c-c4a4-48f6-ba39-ec43dfcb7054/small/12152.jpg)
research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
![Pathways to inflammation: acne pathophysiology](/images/research/3edfe2b4-9d6e-474b-b3a6-38366b2c865e/small/26164.jpg)
research Pathways to inflammation: acne pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
![The Effect of 5 -Reductase Inhibitors on Erectile Function](/images/research/724881f7-9e66-4227-ae68-c5f3ef332f36/small/15056.jpg)
research The Effect of 5 -Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
Community Join
5 / 1000+ resultscommunity Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc
Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.
community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol
The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.
community Nandrolone Replacement Therapy
A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.
community What’s your experience with RU58841?
People shared mixed experiences with RU58841 for hair loss; one person saw no improvement, another had significant gains and uses it with finasteride, while a third had an allergic reaction to the premixed solution. Some mix RU58841 powder into minoxidil themselves.