Search
for

    Did you mean Androgen Receptor?
    Glossary Androgen Receptor

    protein in cells that binds male hormones to regulate genes

    The androgen receptor (AR) is a type of protein found inside cells that binds to androgens, which are male hormones like testosterone and dihydrotestosterone. This binding activates the receptor, allowing it to enter the cell nucleus and influence the expression of specific genes, playing a crucial role in the development and maintenance of male characteristics, as well as in conditions like androgenic alopecia (male pattern baldness).

    Related Terms

    Research 10 of 1000+

    1. Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein Archives of biochemistry and biophysics · 1989 · 24 citations
    2. Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms Fertility and sterility · 2010 · 15 citations
    3. Relative binding affinity of novel steroids to androgen receptors in hamster prostate Journal of Enzyme Inhibition and Medicinal Chemistry · 2005 · 5 citations
    4. Crystallization and preliminary X-ray analysis of the human androgen receptor ligand-binding domain with a coactivator-like peptide and selective androgen receptor modulators Acta crystallographica · 2008 · 1 citations
    5. Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia Journal of Medicinal Chemistry · 2026
    6. QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities Molecular Informatics · 2019
    7. Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus) The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 58 citations
    8. The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function American Journal of Pathology · 2003 · 72 citations
    9. Androgen receptor inhibits the hair follicle induction potential of dermal papilla cells by binding with Tcf4 at the A574 binding site Genes & Diseases · 2022 · 4 citations
    10. SAT-288 Successful Virilization of a PAIS Patient with a Missense Mutation In The Ligand-binding Domain Of The Androgen Receptor with Combined High-dose Testosterone and Aromatase Inhibitor Journal of the Endocrine Society · 2019
    All research results →

    Community 10 of 345

    1. If RU58841 is such an effective anti androgen Reddit · 6 Jan 2024
    2. Topical finasteride might be a lie Reddit · 19 Oct 2023
    3. New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase Reddit · 22 May 2024
    4. Why do I have the feeling that this subreddit is flooded by Kintor employees? Reddit · 21 Aug 2024
    5. Is there a consensus on RU these days? Pyril turned out to be a bust right? Reddit · 13 Mar 2024
    6. Bicalutamide effect on androgens? Reddit · 20 Dec 2020
    7. Pyrilutamide ,the molecule’s true nature Community · 20 Aug 2024
    8. Why was fluridil abandoned and never made past phase 2? Reddit · 7 Apr 2022
    9. How is the GT20029 different to pyrilutamide as an androgenic antagonist Reddit · 14 Jan 2025
    10. How can ketoconazole shampoo block androgen receptor if it's just washed off? Reddit · 11 Nov 2025
    All community results →

    Learn 9 of 12

    1. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
    2. GT20029 Experimental topical drug designed to break down androgen receptors
    3. RU58841 Experimental topical anti-androgen sold as a research chemical
    4. Bicalutamide Nonsteroidal anti-androgen, originally a prostate cancer drug
    5. Neem Oil Oil from the neem tree, used in traditional remedies
    6. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
    7. Pyrilutamide Experimental topical anti-androgen, also known as KX-826
    8. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
    9. Fluridil Topical anti-androgen sold as a cosmetic lotion
    All learn results →