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research Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling

42 citations , July 2017 in “Molecular therapy”

This study found that applying a tocotrienol-rich phytochemical topically induced hair follicle development in adult mice, revealing a new epidermal pathway involving E-cadherin and β-catenin.

research Integrated analysis of lncRNAs and mRNAs by RNA-Seq in secondary hair follicle development and cycling (anagen, catagen and telogen) of Jiangnan cashmere goat (Capra hircus)

24 citations , May 2022 in “BMC Veterinary Research”

This study identified key mRNAs and lncRNAs, along with related pathways, that play potentially important roles in hair follicle development and cycling in cashmere goats.

research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling

65 citations , September 2004 in “The American journal of pathology”

This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.

research Mesenchymal-epidermal interactions in hair follicle cycling and regeneration

May 2015

This study found that STAT5 activation and Sox18 are key in regulating hair follicle induction and cycling, while transducing SKPs with active STAT5B improved wound healing by reducing inflammation.

research Does D matter? The role of vitamin D in hair disorders and hair follicle cycling

98 citations , February 2010 in “Dermatology Online Journal”

This article outlines the potential for upregulating the vitamin D receptor in treating hair disorders, emphasizing the need for further studies to evaluate vitamin D's role in the hair cycle.

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Community Join

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community Scalp Skin Barrier Health and Hair Follicle Cycling: A Potential Overlooked Connection

in Technology 4 months ago

The conversation discusses the importance of scalp skin barrier health in hair follicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community if hair follicle miniaturization happens slowly and gradually over a few hair cycles then wouldn't that mean that to regain maximum or top thickness from treatment you would at least need 5-10 years?

in Research/Science 53 upvotes 10 months ago

Hair regrowth from treatments like finasteride, dutasteride, and minoxidil can take several years, with most visible results appearing within 1-2 years and potential improvements continuing up to 10 years. Consistency and patience are crucial for achieving maximum hair thickness, as hair miniaturization and regrowth are gradual processes.

community In theory, will everyone on setipiprant be able to maintain their hair forever?

4 upvotes 10 years ago

Setipiprant may help with hair maintenance but is not a guaranteed solution for everyone. Other treatments like minoxidil, finasteride, and topical spironolactone are discussed, with varying opinions on their effectiveness.

community Positive Hair Result in Patient using Tirzepatide

4 upvotes 1 year ago

A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.

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Learn

6 / 800 results

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Follistatin

Protein that blocks activin, a growth-regulating signal

learn Caffeine

Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label, manufacturer-funded trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint. A 2025 systematic review found only a few small controlled trials, mostly rated low or very low quality, and none in alopecia areata.

learn Latanoprost

How does latanoprost work to make eyelashes and possibly scalp hair grow? Studies report that latanoprost, a prostaglandin analog, lengthens the anagen (growth) phase of hair follicles, which is the mechanism given for the eyelash thickening seen in glaucoma patients; on the scalp the evidence is one 16-man pilot study and animal work, so the effect there is unproven.

learn Peppermint

herb and oil thought to stimulate skin and hair

learn Dexpanthenol

Provitamin B5, a moisturiser in hair and skin products

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Clinics

2 / 13 results

Hairo Fallas