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    GlossaryActivator Protein 1

    transcription factor regulating gene expression and cellular processes

    Activator Protein 1 (AP-1) is a transcription factor, which means it helps control the expression of certain genes. It is a complex of proteins that binds to specific DNA sequences, thereby regulating processes like cell growth, differentiation, and apoptosis. In the context of hair biology, AP-1 can influence the growth cycle of hair follicles and may play a role in conditions like alopecia.

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Microneedling to maintain results from min

      in Microneedling  7 upvotes 2 months ago
      Microneedling alone is not effective in maintaining minoxidil results for hair growth. Combining microneedling with minoxidil and finasteride may enhance results, but microneedling by itself is not a reliable treatment.