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    GlossaryActivator Protein 1

    transcription factor regulating gene expression and cellular processes

    Activator Protein 1 (AP-1) is a transcription factor, which means it helps control the expression of certain genes. It is a complex of proteins that binds to specific DNA sequences, thereby regulating processes like cell growth, differentiation, and apoptosis. In the context of hair biology, AP-1 can influence the growth cycle of hair follicles and may play a role in conditions like alopecia.

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      community Whey Protein can cause hairloss in men with AGA as per a doctor

      in Research/Science  65 upvotes 3 months ago
      Whey protein may slightly increase hair loss in men with androgenetic alopecia (AGA) due to elevated IGF-1 and testosterone levels, but the effect is minimal compared to treatments like finasteride and dutasteride. Many users argue that whey protein's impact on hair loss is negligible and that maintaining a healthy lifestyle is more important.

      community TDM-105795 phase 2 results are in!

      in Research/Science  29 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  91 upvotes 3 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.