The Myeloid Mineralocorticoid Receptor Regulates Dermal Angiogenesis and Inflammation in Glucocorticoid-Induced Impaired Wound Healing

    Van Tuan Nguyen, Qui Trung Ngô, Roberto Palacios … Frédéric Jaisser
    Studysummary In this study, topical MR blockade improved delayed wound healing in glucocorticoid-pretreated mice by promoting anti-inflammatory macrophages and enhancing angiogenesis.
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    Research cited in this study 5

    1. The Myeloid Mineralocorticoid Receptor Regulates Dermal Angiogenesis and Inflammation in Glucocorticoid-Induced Impaired Wound Healing British Journal of Pharmacology · 2022
    2. Cutaneous Wound Healing in Diabetic Mice Is Improved by Topical Mineralocorticoid Receptor Blockade Journal of Investigative Dermatology · 2019
    3. Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1-Dependent Manner Journal of Investigative Dermatology · 2018
    4. Mineralocorticoid Receptor Antagonists: A New Sprinkle of Salt and Youth Journal of Investigative Dermatology · 2016
    5. Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia American Journal of Pathology · 2007