Thyroid Hormone Action in Epidermal Development and Homeostasis and Its Implications in the Pathophysiology of the Skin

    March 2021 in “ Journal of endocrinological investigation ”
    Giuseppina Mancino, Caterina Miro, Emery Di Cicco, Monica Dentice
    Studysummary This review covers the connection between thyroid diseases and skin conditions like alopecia, dermatitis, and vitiligo, and highlights the need for further research on the role of thyroid hormones in skin health.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 11

    1. Dermatologic Manifestations of Endocrine Disorders Translational pediatrics · 2017
    2. A New Humanized Mouse Model For Alopecia Areata Journal of Investigative Dermatology Symposium Proceedings · 2013
    3. Thyroid Hormone Action on Skin Current Opinion in Endocrinology, Diabetes and Obesity · 2012
    4. Thyroid-Stimulating Hormone: A Novel, Locally Produced Modulator of Human Epidermal Functions, Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones Endocrinology · 2010
    5. Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance Journal of Investigative Dermatology · 2009
    6. Endocrine Controls of Keratin Expression BioEssays · 2009
    7. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008
    8. Location and Phenotype of Human Adult Keratinocyte Stem Cells of the Skin Differentiation · 2004
    9. Expression of Hypothalamic-Pituitary-Thyroid Axis Related Genes in Human Skin Journal of Investigative Dermatology · 2002
    10. Beauty Is Skin Deep: The Fascinating Biology of the Epidermis and Its Appendages PubMed · 2000
    11. Clinical Review 74: Dermatological Manifestations of Endocrine Disorders The Journal of Clinical Endocrinology & Metabolism · 1995