Composite Double-Layer Microneedle Loaded With Traditional Chinese Medicine for the Treatment of Androgenic Alopecia

    February 2023 in “ Medicine in novel technology and devices ”
    Ruoxi Wang, Jiangge Wang, Haiqiang Gao … Xufeng Niu
    Studysummary This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.
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    Research cited in this study 16

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    2. Dissolving Microneedles: Applications and Growing Therapeutic Potential Journal of Controlled Release · 2022
    3. Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model Acta Biomaterialia · 2022
    4. Health-Related Quality of Life, Depression, and Self-Esteem in Patients With Androgenetic Alopecia JAMA Dermatology · 2021
    5. Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia Journal of Controlled Release · 2019
    6. Transcutaneous Implantation of Valproic Acid-Encapsulated Dissolving Microneedles Induces Hair Regrowth Biomaterials · 2018
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    9. Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice Journal of Ethnopharmacology · 2015
    10. Promotion Effect of Constituents from the Root of Polygonum Multiflorum on Hair Growth Bioorganic & Medicinal Chemistry Letters · 2013
    11. Topical Application of Polygonum Multiflorum Extract Induces Hair Growth of Resting Hair Follicles Through Upregulating Shh and β-Catenin Expression in C57BL/6 Mice Journal of Ethnopharmacology · 2011
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    1. Composite Double-Layer Microneedle Loaded With Traditional Chinese Medicine for the Treatment of Androgenic Alopecia Medicine in novel technology and devices · 2023