February 2023 in “Medicine in novel technology and devices” This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.
26 citations
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June 2020 in “Polymers” This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.
64 citations
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May 2019 in “Materials Science and Engineering: C” This review outlines the development, applications, and challenges of microneedle-based drug delivery from 2000-2019, particularly highlighting fabrication techniques, but reports no new clinical results.
February 2025 in “Advanced Composites and Hybrid Materials” This study reported that in animal studies of androgenetic alopecia, a biodegradable microneedle patch releasing glutamic acid promoted hair regeneration more effectively than daily minoxidil, with higher hair follicle counts and less frequent dosing, showing the potential for clinical application.
1 citations
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January 2025 in “BIO Integration” This review highlights that the combination of ultrasound and microneedles can enhance transdermal drug delivery by using physical and energy-driven mechanisms to improve drug penetration into deeper skin layers, with implications for precision medicine and chronic disease treatments.
