Homocysteine in Androgenetic Alopecia: A Case Control Study and Observational Experiments on Mice

    Yao Zhang, Yuan Sheng, Qinping Yang, Yibin Zeng
    Studysummary This study found that higher homocysteine levels were associated with androgenetic alopecia and inhibited hair growth in mice, suggesting a potential link that warrants further investigation.
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    Research cited in this study 16

    1. Regulatory Effects of FGF9 on Dermal Papilla Cell Proliferation in Small-Tailed Han Sheep Genes · 2023
    2. Clinical and Metabolic Characteristics of Males With Early-Onset Androgenetic Alopecia PubMed · 2022
    3. Impaired Cardiometabolic Effects of Bromocriptine in Men With Early-Onset Androgenic Alopecia The Journal of Clinical Pharmacology · 2022
    4. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    5. The Inflammatory Component of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
    6. Impact of Lisinopril on Cardiometabolic Risk Factors in Men with Hypertension and Early-Onset Androgenetic Alopecia Journal of Cardiovascular Pharmacology · 2021
    7. MTHFR C677T Polymorphism and Serum Homocysteine Level as Risk Factors of Coronary Heart Disease in Patients with Androgenetic Alopecia: A Case-Control Study The American Journal of the Medical Sciences · 2021
    8. Cardiometabolic Risk Factors in Rosuvastatin-Treated Men with Mixed Dyslipidemia and Early-Onset Androgenic Alopecia Molecules · 2021
    9. Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture Frontiers in Pharmacology · 2020
    10. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    11. Exogenous Stimulation with Eclipta Alba Promotes Hair Matrix Keratinocyte Proliferation and Downregulates TGF-β1 Expression in Nude Mice International Journal of Molecular Medicine · 2014
    12. Evaluation of Serum Homocysteine, High-Sensitivity CRP, and RBC Folate in Patients with Alopecia Areata Indian Journal of Dermatology · 2014
    13. Activin B Promotes Initiation and Development of Hair Follicles in Mice Cells Tissues Organs · 2013
    14. Androgenetic Alopecia and Risk of Coronary Artery Disease Indian Dermatology Online Journal · 2013
    15. Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study Journal of The American Academy of Dermatology · 2010
    16. Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men Mayo Clinic Proceedings · 2005