Demographic Characteristics and Association of Serum Vitamin B12, Ferritin, and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases

    Sidharth Sonthalia, A Santhi Priya, Desmond J. Tobin
    Studysummary This study found that premature hair graying is strongly associated with a family history, Vitamin B12 deficiency, and hypothyroidism, with onset as early as 5 years in patients in Gurugram, India.
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    Research cited in this study 8

    1. Premature Graying of Hair: Causes, Associations, and Treatments Indian Journal of Dermatology, Venereology and Leprology · 2013
    2. Epidemiological and Investigative Study of Premature Graying of Hair in Higher Secondary and Pre-University School Children International Journal of Trichology · 2013
    3. The Degree of Premature Hair Graying as an Independent Risk Marker for Coronary Artery Disease: A Predictor of Biological Age Rather Than Chronological Age The Anatolian journal of cardiology · 2012
    4. Serum Iron, Zinc, and Copper Concentration in Premature Graying of Hair Biological trace element research · 2011
    5. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    6. Pharmacologic Interventions in Aging Hair Clinical Interventions in Aging · 2006
    7. Segmented Heterochromia in Black Scalp Hair Associated With Iron-Deficiency Anemia Archives of Dermatology · 1989
    8. Reversible Hyperpigmentation of Skin and Nails With White Hair Due to Vitamin B12 Deficiency Archives of Dermatology · 1986