The Biology of Hair Follicles

    August 1999 in “ The New England Journal of Medicine ”
    Ralf Paus, George Cotsarelis
    Studysummary This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
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    Research cited in this study 20

    1. Splitting Hairs: Molecular Mechanisms of Hair and Feather Development Cell · 1998
    2. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    3. Hair Growth Cycle Affects Hair Follicle Destruction by Ruby Laser Pulses Journal of Investigative Dermatology · 1998
    4. Towards Defining the Pathogenesis of the Hairless Phenotype Journal of Investigative Dermatology · 1998
    5. The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    6. Alopecia Universalis Associated With a Mutation in the Human Hairless Gene Science · 1998
    7. Hoxc13 Mutant Mice Lack External Hair Genes & Development · 1998
    8. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    9. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997
    10. Clinical Updates in Hair Dermatologic Clinics · 1997
    11. Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque Endocrinology · 1997
    12. Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy Molecular Medicine Today · 1996
    13. Dermal-Epidermal Interactions in Hair Follicle Development and Maintenance Dermatologic clinics · 1996
    14. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996
    15. Regulation of Human Dermal Papilla Cell Production of Insulin-Like Growth Factor Binding Protein-3 by Retinoic Acid, Glucocorticoids, and Insulin-Like Growth Factor-1 Journal of cellular physiology · 1996
    16. Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure. The EMBO Journal · 1995
    17. Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    18. Biochemical Mechanisms Regulating Human Hair Growth Skin Pharmacology and Physiology · 1994
    19. Telogen Effluvium: New Concepts and Review Archives of Dermatology · 1993
    20. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 6

    1. Alopecia in Women Revista brasileira de medicina · 2013
    2. Congenital Hair Loss Disorders: Rare, But Not Too Rare The Journal of Dermatology · 2011
    3. Alopecia Journal of the Korean Medical Association · 2002
    4. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    5. Diseases of the Hair and Scalp Archives of Dermatology · 1994
    6. Disorders of Hair Growth: Diagnosis and Treatment McGraw-Hill eBooks · 1994