Role of Vitamin D and Calcium in Epidermal Wound Repair

    December 2017 in “ Wound healing ”
    Daniel D Bikle, Chia-Ling Tu, Yuko Oda … Yuko Oda
    Studysummary This study found that vitamin D and calcium signaling are essential for effective wound repair by maintaining and activating stem cells and aiding in their migration and differentiation.
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    Research cited in this study 17

    1. Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization Endocrinology · 2017
    2. Vitamin D And Calcium Regulation Of Epidermal Wound Healing The Journal of Steroid Biochemistry and Molecular Biology · 2015
    3. The Vitamin D Receptor Is Required for Activation of CWnt and Hedgehog Signaling in Keratinocytes Molecular Endocrinology · 2014
    4. Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice PloS one · 2014
    5. In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators Nature Cell Biology · 2014
    6. Lineage Analysis of Epidermal Stem Cells Cold Spring Harbor Perspectives in Medicine · 2014
    7. Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche Nature Reviews Molecular Cell Biology · 2013
    8. Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-Beta Signaling During the Inflammatory Response to Cutaneous Injury Endocrinology · 2012
    9. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012
    10. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    11. The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but Not for Maintenance of the Epidermal Stem Cell Compartment ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    12. The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008
    13. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    14. Vitamin D Receptor Is Essential For Normal Keratinocyte Stem Cell Function Proceedings of the National Academy of Sciences · 2007
    15. Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse Journal of cellular physiology · 2006
    16. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    17. Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002

    Related research 1

    1. The Effect of Flavonoids on Regenerated Hair Follicles with Pigmentation Journal of Dermatological Science · 2017