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Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny During Cutaneous Wound Repair

research Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair

46 citations , May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that the vitamin D receptor is essential for the self-renewal, migration, and differentiation of epidermal stem cells during skin wound healing in mice.

research Role of Vitamin D and Calcium in Epidermal Wound Repair

1 citations , December 2017 in “Wound healing”

This study found that vitamin D and calcium signaling are essential for effective wound repair by maintaining and activating stem cells and aiding in their migration and differentiation.

research Necl2 regulates epidermal adhesion and wound repair

35 citations , September 2009 in “Development”

This study found that overexpression of the intercellular adhesion protein Necl2 in hair follicle stem cells was associated with reduced cell proliferation and delayed wound healing in both cultured cells and transgenic mice.

Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair

research Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair

204 citations , October 1999 in “EMBO journal”

This study found that overexpression of activin in transgenic mice led to enhanced granulation tissue formation after skin injury due to changes in keratinocyte proliferation and differentiation.

research Effect of Flightless I Expression on Epidermal Stem Cell Niche During Wound Repair

10 citations , July 2019 in “Advances in Wound Care”

This study suggests that Flightless I may inhibit the activation of epidermal stem cells during wound repair by disrupting Wnt/β-catenin signaling, potentially delaying wound reepithelialization.

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Community Join

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community Another molecular pathway to promote scarless healing and regenerate hair follicles

14 upvotes 8 months ago

Carnosic acid in rosemary extract may enhance skin repair and promote hair follicle regeneration. It could be used alone or with verteporfin for scarless healing after dermal wounding.

community Scalp slapping to increase blood flow?

in Treatment 22 upvotes 2 years ago

This post and conversation are about using scalp slapping to increase blood flow for hair growth. One user suggests using minoxidil instead.

community Summary of Procapil video by Haircafe

2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 1 year ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

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Learn

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learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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Hair Loss TreatmentsDermatology
SkinSol Dermatology & Aesthetics + Wound Care CenterBoca Raton, FL · US

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