Cutaneous Manifestations of Endocrine Disease

November 2019 in “ Harper's Textbook of Pediatric Dermatology ”

Devika Icecreamwala, Tor Shwayder

Pediatric endocrine diseases were associated with various cutaneous manifestations. Hypothyroidism led to xerosis, skin thickening, and brittle hair, while hyperthyroidism caused facial flushing and moist skin. Elevated cortisol levels resulted in skin thinning and acne, and adrenal insufficiency caused hyperpigmentation. Androgen excess was linked to acne and increased hair growth, and hyperoestrogenism to gynaecomastia. Hypopituitarism caused skin wrinkling, whereas hyperpituitarism was linked to gigantism/acromegaly. Hypoparathyroidism resulted in dry skin and alopecia, and primary hyperparathyroidism caused dehydration and dry mucous membranes.

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