Cutaneous Manifestations of Endocrine Disease
November 2019
in “
Harper's Textbook of Pediatric Dermatology
”
hypothyroidism hyperthyroidism elevated cortisol levels adrenal insufficiency androgen excess hyperoestrogenism hypopituitarism hyperpituitarism hypoparathyroidism primary hyperparathyroidism alopecia xerosis brittle hair skin thickening facial flushing moist skin skin thinning acne hyperpigmentation increased hair growth gynaecomastia skin wrinkling gigantism acromegaly dehydration dry mucous membranes dry skin thick skin flushed face thin skin hair loss excess hair growth breast enlargement wrinkled skin giant growth dry mouth
TLDR Endocrine diseases in children can cause various skin and hair changes.
The document discussed how pediatric endocrine diseases could lead to various cutaneous manifestations. Congenital and acquired hypothyroidism were associated with skin thickening and brittle hair, while hyperthyroidism often resulted in facial flushing and moist skin. Increased cortisol levels could cause acne and skin thinning, and adrenal insufficiency was linked to hyperpigmentation. Androgen excess might lead to acne and increased hair growth, whereas hyperoestrogenism was associated with gynaecomastia. Hypopituitarism could cause skin wrinkling, and hyperpituitarism was linked to gigantism/acromegaly. Hypoparathyroidism could result in alopecia and brittle nails, while primary hyperparathyroidism might cause dehydration and dry mucous membranes.