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research Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review

35 citations , April 2013 in “Sexual medicine reviews”

This review found that 5α-reductase inhibitors are associated with slightly increased rates of sexual dysfunction, gynecomastia, and mood disorders, but the true significance and persistence of these effects remain unclear.

Medical Consequences of Long-Term Anabolic-Androgenic Steroid Abuse in Athletes

research Medical consequences of long-term anabolic-androgenic Steroids (AASs) abuses in athletes

5 citations , January 2017 in “Biomedical Research-tokyo”

This review examines the long-term health risks of anabolic-androgenic steroid abuse in athletes, reporting various physical and psychological side effects without sufficient benefits.

research Cutaneous Manifestations of Endocrine Disease

4 citations , November 2019 in “Harper's Textbook of Pediatric Dermatology”

This article reviews the skin, hair, nail, and mucosal changes linked to various pediatric endocrine disorders but provides no new clinical findings.

research GYNECOMASTIA AFTER FINASTERIDE THERAPY

3 citations , October 1995 in “Southern Medical Journal”

Finasteride may cause breast enlargement, low testosterone a risk factor.

Tolerance of Spironolactone in Acne and Hirsutism Treatment

research (13) Tolerance of spironolactone

1 citations , June 1987 in “British journal of dermatology/British journal of dermatology, Supplement”

This study found that despite a high incidence of side effects, patients generally tolerated spironolactone while benefiting from its treatment effects for acne and hirsutism.

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Community Join

5 / 283 results

community Serenoa repens (Saw palmetto)

3 upvotes 6 months ago

Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

community PSA: Not all Finasteride generics are created equal, effectiveness and severity of side-effects can vary by manufacturer.

1 year ago

Switching generic finasteride manufacturers can reduce side effects while maintaining effectiveness. Different fillers in generics may affect bioavailability and cause varying side effects.

community When did your regrowth level out?

in Treatment 58 upvotes 10 months ago

Hair regrowth typically levels out after several months of treatment with finasteride, dutasteride, and minoxidil, with many users experiencing stabilization rather than significant regrowth. Starting treatment early is crucial, as regrowth is rare beyond Norwood 3 without additional interventions like hair transplants.

community One year off fin/min and I regret it

416 upvotes 1 year ago

The user regrets stopping finasteride and minoxidil due to side effects but plans to resume treatment. They consider using finasteride every other day and continuing topical minoxidil to manage side effects while maintaining hair.

community A science based addition to your hair loss routine

in Research/Science 23 upvotes 2 years ago

Blocking the Mitochondrial pyruvate carrier and using aldose reductase inhibitors like Indian gooseberry and berberine may help with hair growth. Magnesium can also be added to increase NADPH.

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Learn

2 / 801 results

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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