The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs

    June 2019 in “ eLife ”
    Leah Guthrie, Sarah J. Wolfson, Libusha Kelly
    Studysummary This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
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    Research cited in this study 3

    1. Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version Journal of Dermatology · 2018
    2. In Vitro Analysis of Finasteride Activity Against Candida Albicans Urinary Biofilm Formation and Filamentation Antimicrobial Agents and Chemotherapy · 2014
    3. Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model Urologia Internationalis · 2011