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research The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

36 citations , June 2019 in “eLife”

This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.

research 1397 LSD1 is critical for epidermal development and skin barrier formation

April 2023 in “Journal of Investigative Dermatology”

This study found that LSD1 is crucial for embryonic skin barrier formation in mice, revealing its significant role in epidermal development and suggesting its potential as a target in skin diseases with barrier defects.

research The Role of Histone Demethylases in Disease

1 citations , January 2011 in “Springer eBooks”

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

research Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

667 citations , May 2008 in “Genes & Development”

This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.

A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

research A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long Term Side Effects after Finasteride Discontinuation

16 citations , September 2014 in “International Journal of Biological Markers”

This study found that the less common CAG-rs4045402 and GGN-rs3138869 polymorphisms were more frequent in patients with post-finasteride syndrome and androgenetic alopecia, suggesting a genetic predisposition to AGA development.

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Clinical Trial: N-Acetyl-Cysteine for Treatment of AGA in Men

5 upvotes 5 years ago

N-Acetyl-Cysteine (NAC) is being explored for treating hair loss, but users report mixed results. Some also mention using Quercetin and Resveratrol without significant hair improvement.

community Minokem-N cotains hydrocortisone?

2 upvotes 1 year ago

Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

community What's the deal with Spectral.DNC-N/'nanoxidil'?

4 upvotes 3 years ago

Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.

community Has anyone here tried Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster?

in Technology 1 upvotes 6 months ago

The conversation discusses the effectiveness of Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster for hair shedding and thinning. The main ingredient, Aminexil, is compared to Minoxidil, and the user seeks real experiences to determine its efficacy.

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