Platelet-Rich Plasma Versus Topical 5% Minoxidil in the Treatment of Androgenetic Alopecia: A Comparative Observational Study

    December 2025
    Studysummary This study found that platelet-rich plasma therapy led to greater improvements in hair density and patient satisfaction compared to topical 5% Minoxidil in androgenetic alopecia patients over 12 weeks.
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    Research cited in this study 10

    1. Comparison of the Efficacy of Platelet-Rich Plasma With Topical Minoxidil in Treating Patients With Androgenetic Alopecia: A Systematic Review of Clinical Trials Skin Health and Disease · 2025
    2. Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in Treating Alopecia Areata: A Head-to-Head Assessment of Novel Approaches Cureus · 2024
    3. Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study Cureus · 2024
    4. A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2022
    5. Combination Therapy with Platelet-Rich Plasma and Minoxidil Leads to Better Clinical Results Than Monotherapy in Men with Androgenetic Alopecia International Journal of Trichology · 2022
    6. Comparison of 5% Minoxidil Lotion Monotherapy Versus Its Combination with Autologous Platelet-Rich Plasma in Androgenetic Alopecia in One Hundred Males Medical journal, Armed Forces India · 2021
    7. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    8. A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia International Journal of Trichology · 2019
    9. A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia International Journal of Trichology · 2017
    10. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002