Platelet-Rich Plasma Versus Topical 5% Minoxidil in the Treatment of Androgenetic Alopecia: A Comparative Observational Study

January 2025

platelet-rich plasma topical 5% minoxidil androgenetic alopecia hair density follicular strengthening growth factor-mediated stimulation PRP Rogaine

TLDR PRP therapy improves hair density and satisfaction more than Minoxidil for androgenetic alopecia.

This study compared the efficacy of Platelet-Rich Plasma (PRP) therapy and topical 5% Minoxidil in treating androgenetic alopecia over 12 weeks, involving 50 patients. The PRP group showed a significantly greater increase in hair density and higher patient satisfaction compared to the Minoxidil group. PRP led to an earlier reduction in hair shedding and better follicular strengthening, likely due to growth factor-mediated stimulation. Both treatments were well-tolerated with mild adverse effects. The study concludes that PRP therapy offers superior improvement in hair density and patient satisfaction, suggesting it as an effective option for early to moderate androgenetic alopecia, though larger studies are needed to validate these findings.

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Research cited in this study

10 / 10 results

research Comparison of the Efficacy of Platelet-Rich Plasma With Topical Minoxidil in Treating Patients With Androgenetic Alopecia: A Systematic Review of Clinical Trials

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research Combination Therapy with Platelet-Rich Plasma and Minoxidil Leads to Better Clinical Results Than Monotherapy in Men with Androgenetic Alopecia

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research A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia

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research Comparison of 5% Minoxidil Lotion Monotherapy Versus Its Combination with Autologous Platelet-Rich Plasma in Androgenetic Alopecia in One Hundred Males

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research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy

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research A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia

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PRP therapy works better than minoxidil for treating hair loss.

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research A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

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Platelet-Rich Plasma Versus Topical 5% Minoxidil in the Treatment of Androgenetic Alopecia: A Comparative Observational Study

Research cited in this study

research Comparison of the Efficacy of Platelet-Rich Plasma With Topical Minoxidil in Treating Patients With Androgenetic Alopecia: A Systematic Review of Clinical Trials

research Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in Treating Alopecia Areata: A Head-to-Head Assessment of Novel Approaches

research Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study

research Combination Therapy with Platelet-Rich Plasma and Minoxidil Leads to Better Clinical Results Than Monotherapy in Men with Androgenetic Alopecia

research A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia

research Comparison of 5% Minoxidil Lotion Monotherapy Versus Its Combination with Autologous Platelet-Rich Plasma in Androgenetic Alopecia in One Hundred Males

research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy

research A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia

research A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

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