Platelet-Rich Plasma and Topical Finasteride for Androgenic Alopecia: A Case Study

December 2022 in “ Dermatologie pro praxi ”

Markéta Fridman, M A.

platelet-rich plasma topical finasteride androgenic alopecia topical minoxidil hair regrowth PRP Propecia Rogaine

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary In this case study, a combination of PRP, topical minoxidil, and topical finasteride showed significantly better results in treating androgenic alopecia than minoxidil alone for a 35-year-old male patient.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This case study discusses a 35-year-old male with androgenic alopecia who had minimal results after 3 years of treatment with topical minoxidil. The patient then received 2 applications of platelet-rich plasma (PRP) combined with topical minoxidil and topical finasteride, resulting in significant hair regrowth within 3 months. The combined treatment of PRP, topical minoxidil, and topical finasteride proved significantly more effective than topical minoxidil alone for this patient.

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Research cited in this study

11 / 11 results

research Platelet-Rich Plasma in Female Androgenic Alopecia: A Comprehensive Systematic Review and Meta-Analysis

7 citations , May 2021 in “Frontiers in Pharmacology”

This review highlights platelet-rich plasma as a promising nonsurgical treatment for female pattern hair loss, but it reports no new clinical results.

research Platelet-Rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-Controlled Pilot Study

8 citations , January 2020 in “Acta dermato-venereologica”

This pilot study found that platelet-rich plasma injections did not improve hair growth in men with androgenetic alopecia.

Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons

research Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons

22 citations , October 2018 in “Aesthetic Plastic Surgery”

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels

research Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels

57 citations , October 2018 in “Journal of The American Academy of Dermatology”

This study found that platelet-rich plasma significantly increased hair count, density, and the percentage of anagen hairs in patients with androgenetic alopecia, but these improvements did not correlate with platelet or growth factor levels.

research Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol

45 citations , September 2018 in “International Journal of Women's Dermatology”

This review discusses the use of platelet-rich plasma as a treatment for androgenetic alopecia and highlights the need for standardized protocols, reporting no new clinical results.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia

research Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia

42 citations , December 2015 in “International Journal of Clinical Pharmacology and Therapeutics”

This study found that applying a novel 0.25% finasteride solution to the scalp can effectively reduce scalp DHT levels in men with androgenetic alopecia, potentially reducing systemic side-effects.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , March 2012 in “Dermatologic Surgery”

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.

research Comparing the Therapeutic Effects of Finasteride Gel and Tablet in Treatment of Androgenetic Alopecia

57 citations , January 2009 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that both topical and oral finasteride had similar therapeutic effects in treating male androgenic alopecia, with no significant differences in hair thickness, counts, or bald area size.

research Medical Treatments for Male and Female Pattern Hair Loss

212 citations , September 2008 in “Journal of The American Academy of Dermatology”

This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.

research Molecular Mechanisms of Androgenetic Alopecia

229 citations , August 2002 in “Experimental Gerontology”

This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.