Evaluation of the Effect of Piperonylic Acid on Wound Healing in Mice

    December 2020
    Karina Moreira
    Studysummary In this study, topical application of piperonylic acid was observed to accelerate wound healing in mice by enhancing EGFR activation, keratinocyte modulation, and collagen deposition, suggesting its potential as a treatment for skin injuries.
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    Research cited in this study 5

    1. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    2. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated With Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016
    3. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    4. Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice Experimental Dermatology · 2014
    5. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007