Efficacy of Oxygen-Enriched Platelet-Rich Plasma Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Retrospective Study

    July 2026 in “ Journal of Cosmetic Dermatology ”
    Jianyun Lu, Tong Zhang, D Wang … Lihua Gao
    Studysummary This study found that combining oxygen-enriched PRP with minoxidil significantly improved hair density, hair diameter, and follicular density in patients with androgenetic alopecia compared to minoxidil alone, with higher satisfaction scores and only mild, transient adverse effects.
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    Research cited in this study 15

    1. Research Progress on Platelet-Rich Plasma (PRP) in the Treatment of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2026
    2. Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment Drug Design Development and Therapy · 2025
    3. Comparative Efficacy of Minoxidil Alone Versus Minoxidil Combined With Low-Level Laser Therapy in the Treatment of Androgenic Alopecia: A Systematic Review and Meta-Analysis Journal of Dermatological Treatment · 2025
    4. Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study Cureus · 2024
    5. Effect of Platelet Counts and Activator in Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia, Split-Head Comparison: A Randomised, Double-Blind Study Indian Journal of Dermatology, Venereology and Leprology · 2023
    6. The Effectiveness of Low-Level Light/Laser Therapy on Hair Loss Facial plastic surgery & aesthetic medicine · 2021
    7. Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia International Journal of Molecular Sciences · 2020
    8. The Effectiveness of Combination Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Dermatologic Therapy · 2020
    9. Autologous Activated Platelet-Rich Plasma (AA-PRP) and Non-Activated (A-PRP) in Hair Growth: A Retrospective, Blinded, Randomized Evaluation in Androgenetic Alopecia Expert Opinion on Biological Therapy · 2020
    10. Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia BioMed Research International · 2020
    11. Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation Biomedicines · 2019
    12. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    13. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    14. Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017
    15. Clinical Severity Does Not Reliably Predict Quality of Life in Women With Alopecia Areata, Telogen Effluvium, or Androgenic Alopecia Journal of The American Academy of Dermatology · 2011