Premature Aging and Cancer Development in Transgenic Mice Lacking Functional CYLD

    January 2019 in “ Aging ”
    Josefa P. Alameda, Ángel Ramı́rez, Rosa A. García‐Fernández … M. Casanova
    Studysummary This study found that transgenic mice expressing a mutant CYLD protein lacking deubiquitinase function showed signs of premature aging and spontaneous tumor development, likely due to over-activation of specific molecular pathways and chronic inflammation.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on aging-us.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Aging of Hair Journal of Cosmetic Dermatology · 2005
    2. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001
    3. Growth of the Hair Physiological Reviews · 1954