Two Mutations at KRT74 and EDAR Synergistically Drive the Fine-Wool Production in Chinese Sheep

May 2023 in “ Journal of Advanced Research ”

Benmeng Liang, Tianyou Bai, Yuzu Zhao, Jiangang Han, Xiaohong He, Pu Yun, Chunxin Wang, Wujun Liu, Qing Ma, Kechuan Tian, Wenjie Zheng, Nan Liu, Jianfeng Liu, Yuehui Ma, Lin Jiang

KRT74 EDAR missense variant SNP hair follicle density single nucleotide polymorphism

Studysummary In this study, researchers identified two genetic mutations associated with producing finer and denser wool in fine-wool sheep, involving the genes KRT74 and EDAR, which may guide future breeding efforts to enhance wool quality.

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