Minoxidil
January 1993
in “Dermatologic Clinics”
TLDR Minoxidil effectively treats hair loss, works better for women, and requires consistent use.
This document from 30 years ago compiles various studies and research on the use of minoxidil for hair growth and alopecia treatment. The studies suggest that minoxidil can be an effective treatment for hair loss, but further research is needed to fully understand its mechanisms of action and potential side effects. Minoxidil appears to be more effective in women than in men, increasing the number of hairs and hair shaft diameter, which is more useful in a woman's long hair. Compliance is key for effectiveness in both men and women, but minoxidil appears to be more effective in women than in men.
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Cited in this study
research Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro
Minoxidil slows down keratinocyte growth without being toxic.
research Contact dermatitis in reaction to 2% topical minoxidil solution
Minoxidil solution can cause skin irritation and allergies in some users.
research Minoxidil Sulfate Is the Active Metabolite that Stimulates Hair Follicles
Minoxidil sulfate stimulates hair growth.
research Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution
Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
research The Effect of Topical Minoxidil on Hair Follicular Cycles of Rats
Minoxidil speeds up hair growth in rats without prolonging growth phase.
research Five-year follow-up of men with androgenetic alopecia treated with topical minoxidil
Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.
research Influence of tretinoin on the percutaneous absorption of minoxidil from an aqueous topical solution
Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.
research Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture
Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
research Topical minoxidil: cardiac effects in bald man.
Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.
research Allergic contact dermatitis from Minoxidil
Some patients using Minoxidil for baldness developed allergic skin reactions.
research Topical Minoxidil Therapy for Androgenetic Alopecia
The document concludes that topical minoxidil therapy is safe and effective in promoting hair growth for male pattern baldness.
research Topical minoxidil in male pattern baldness: Effects of discontinuation of treatment
Stopping minoxidil treatment resumes balding; continuous use needed for results.
research Dose-response study of topical minoxidil in male pattern alopecia
Minoxidil 1% and 2% best promote hair growth and may prevent hair loss.
research Safety and efficacy of topical minoxidil in the management of androgenetic alopecia
Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.
research Androgenetic alopecia: Treatment results with topical minoxidil
Topical minoxidil is a safe and effective treatment for hair loss caused by androgenetic alopecia.
research Androgenetic Alopecia Treated With Topical Minoxidil
Using minoxidil on balding men's scalps can increase hair growth, according to a 12-month study.
research Use of Topical Minoxidil in the Treatment of Male Pattern Baldness
Minoxidil effectively regrows hair in male pattern baldness.
research Long-term efficacy of topical minoxidil in male pattern baldness
Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
research Hypertrichosis and Congenital Anomalies Associated With Maternal Use of Minoxidil
Minoxidil use during pregnancy can cause excessive hair growth and multiple birth defects in the baby.
research Topical minoxidil in early androgenetic alopecia
Using minoxidil on balding scalps can stimulate hair regrowth and increase blood flow. It's an effective treatment for early hair loss.
research Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action
Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
research Topical Minoxidil in Extensive Alopecia areata, Including 3-Year Follow-Up
Topical minoxidil effectively and safely treats extensive alopecia areata but doesn't change its course.
research Topical tretinoin for hair growth promotion
Tretinoin may help hair growth and works better when combined with minoxidil.
research Dose-response study of topical minoxidil in male pattern baldness
Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
research The stumptailed macaque as a model for baldness: effects of minoxidil
Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.
research Topical Minoxidil Dose-Response Effect in Alopecia Areata
Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.
research Percutaneous Absorption of Minoxidil in Man
Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
research Reversal of Baldness in Patient Receiving Minoxidil for Hypertension
Minoxidil helped bald patient regrow hair.
research Minoxidil: right atrial cardiac pathology in animals and in man.
Minoxidil may cause heart issues in animals and humans.
research Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex
Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.
Related
research Ethnopharmacological Review of Medicinal Plants for the Treatment of Alopecia
Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.
research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil
Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss
Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.
research Male Androgenetic Alopecia
research Androgenetic alopecia and its remedies – a review
research Sensitization to saw palmetto and minoxidil in separate topical extemporaneous treatments for androgenetic alopecia
Saw palmetto causes allergic reaction, minoxidil causes skin irritation; use cautiously for hair loss.
research Topical minoxidil in male pattern baldness: Effects of discontinuation of treatment
Stopping minoxidil treatment resumes balding; continuous use needed for results.