Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports

    TLDR Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.
    Melatonin, a hormone primarily known for regulating sleep, has potential therapeutic uses in dermatology due to its antioxidant, cytoprotective, immunomodulatory, and anti-apoptotic effects. It has shown positive results in treating atopic dermatitis, hyperpigmentation disorders, and scalp disorders like androgenic alopecia and telogen effluvium. Melatonin can also be used for photoprotection, skin aging prevention, and skin regeneration. It has potential therapeutic applications in oral cavity diseases like periodontitis, reducing pocket depth and clinical loss of attachment. However, its use is not recommended for bronchial asthma due to its pro-inflammatory effect. Despite its potential, melatonin has not yet become a mainstay in dermatological therapy, and more research is needed to further understand its role in dermatology.
    View this study on →

    Cited in this study

      research Natural products for male androgenetic alopecia

      2 citations, January 2022 in “Dermatologic Therapy”
      Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.

      research Protective Effects of Melatonin on the Skin: Future Perspectives

      44 citations, October 2019 in “International Journal of Molecular Sciences”
      Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.