Long-Term Efficacy and Safety of Dutasteride 0.5 mg in Korean Men with Androgenetic Alopecia: 5-Year Data Demonstrating Clinical Improvement with Sustained Efficacy

February 2024 in “ The Journal of Dermatology ”

Seung-Kwon Choi, Soon Hyo Kwon, Woo‐Young Sim, Bark Lynn Lew

dutasteride androgenetic alopecia BASP classification AGA

TLDR Dutasteride 0.5 mg is safe and effective for long-term use in Korean men with hair loss.

The study "Long‐term efficacy and safety of dutasteride 0.5 mg in Korean men with androgenetic alopecia: 5‐year data demonstrating clinical improvement with sustained efficacy" conducted a retrospective analysis on 99 male patients aged 18 and above suffering from androgenetic alopecia (AGA). These patients were treated with dutasteride 0.5 mg for at least 5 years from October 2009 to December 2016. The results showed that 89.9% (89/99) of the patients saw improvement, and 93.9% (93/99) experienced prevention of disease progression. According to the BASP classification, 52.5% (52/99) of the basic type, 75% (15/20) of the specific F type, and 82.2% (60/73) of the specific V type showed clinical improvement after 5 years of treatment. The study concluded that dutasteride demonstrated long-term safety and efficacy in Korean male patients with AGA over a period of at least 5 years.

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Research cited in this study

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Related Community Posts Join

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community AGA evaluation and first steps - BEGINNER MEGAPOST

in Chat 73 upvotes 2 months ago

The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.

community Diffuse hair loss and scalp biopsies

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Be careful when switching from Finasteride to Dutasteride because for more efficacy.

in Finasteride/Dutasteride 13 upvotes 1 month ago

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

community Why does it seem everyone favors finasteride over dutasteride?

in Female 62 upvotes 6 months ago

The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

community Just to show you the superiority of dutasteride over finasteride (it's huge)

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Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community New Dutasteride Long Term Study (5 years) it works.

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The conversation discusses a five-year study on dutasteride, a medication for male hair loss. The study found that 89.9% of patients saw improvement or prevention of hair loss progression, with varying success rates based on different balding patterns. Side effects were mostly sexual and decreased over time. Dutasteride was concluded to be a long-term, safe, and effective treatment for male hair loss.

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