Long-Term Efficacy and Safety of Dutasteride in Korean Men With Androgenetic Alopecia: 5-Year Follow-Up Data
September 2023
in “
Journal of The American Academy of Dermatology
”
Studysummary In this study, researchers observed that after 5 years of treatment, 89.9% of Korean men with androgenetic alopecia experienced improvement and 93.9% had prevention of disease progression with dutasteride 0.5mg, though sexual-related symptoms were common early but subsided over time.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study "Long-term efficacy and safety of dutasteride in Korean men with androgenetic alopecia: 5-year follow-up data exhibiting clinical improvement with sustained efficacy" investigated the 5-year efficacy and safety of dutasteride 0.5mg in 99 Korean men with androgenetic alopecia (AGA). After 5 years of treatment, 89.9% of patients showed improvement or prevention of disease progression, and 93.9% respectively. According to the basic and specific (BASP) classification, 52.5% of the basic type, 75% of the specific F type, and 83.3% of the specific V type showed improvement after 5 years of treatment with a decrease in the grades of the basic and/or specific type compared to baseline. The most common adverse events were sexual related symptoms within the first 6 months of the treatment period which subsided spontaneously. The study concluded that dutasteride exhibited long-term safety and efficacy in male AGA patients, with comparable outcomes to long-term studies evaluating the efficacy of finasteride in male AGA patients.
