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    Comparison of Finasteride, Metformin, and Finasteride Plus Metformin in PCOS

    January 2017 in “ Acta Endocrinologica ”
    Halit Diri, Fahri Bayram, Yilmaz Simsek … Dursun Kocer
    Studysummary This study found that both finasteride and metformin effectively reduced androgen levels and insulin resistance parameters in women with PCOS, without clear evidence of one treatment being superior.
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    Research cited in this study 20

    1. The Polycystic Ovary Syndrome: A Position Statement from the European Society of Endocrinology European Journal of Endocrinology · 2014
    2. Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline The Journal of Clinical Endocrinology and Metabolism · 2013
    3. Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study The Journal of Clinical Endocrinology and Metabolism · 2013
    4. Metformin: An Old Medication of New Fashion: Evolving New Molecular Mechanisms and Clinical Implications in Polycystic Ovary Syndrome European journal of endocrinology · 2009
    5. Finasteride Treatment for One Year in 35 Hirsute Patients Experimental and Clinical Endocrinology & Diabetes · 2009
    6. Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review Endocrine Reviews · 2008
    7. Insulin Sensitizers for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials The Journal of Clinical Endocrinology & Metabolism · 2008
    8. Finasteride Versus Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism International journal of gynaecology and obstetrics · 2004
    9. A Comparison Between Spironolactone and Spironolactone Plus Finasteride in the Treatment of Hirsutism European journal of endocrinology · 2004
    10. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS) Human Reproduction · 2003
    11. The Pathophysiology of Polycystic Ovary Syndrome Clinical endocrinology · 2003
    12. Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2003
    13. The Evaluation and Management of Hirsutism Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology · 2003
    14. Comparison of High-Dose Finasteride (5 mg/day) Versus Low-Dose Finasteride (2.5 mg/day) in the Treatment of Hirsutism European journal of endocrinology · 2002
    15. The Effect of Metformin on Hirsutism in Polycystic Ovary Syndrome European journal of endocrinology · 2002
    16. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2001
    17. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2000
    18. Usefulness of a 12-Month Treatment with Finasteride in Idiopathic and Polycystic Ovary Syndrome-Associated Hirsutism PubMed · 1999
    19. Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994
    20. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994

    Related research 6

    1. Comparison of Clinical and Biochemical Markers of Hirsutism in Polycystic Ovary Syndrome: A Study from a Teaching Hospital in Sri Ramachandra Institute, Chennai, India Journal of evolution of medical and dental sciences · 2021
    2. Comparison of Finasteride, Metformin, and Finasteride Plus Metformin in PCOS Acta Endocrinologica · 2017
    3. Is It Necessary to Measure Free Testosterone to Assess Hyperandrogenemia in Women? The Role of Calculated Free and Bioavailable Testosterone Experimental and Clinical Endocrinology & Diabetes · 2006
    4. Bioactive and Peripheral Androgens in Prepubertal Simple Hypertrichosis Clinical Endocrinology · 1990
    5. Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia Clinical Endocrinology · 1990
    6. The Influence of Androgens on Insulin Resistance Fertility and sterility · 1984