Rates of Infections, Malignancies, Cardiovascular Outcomes, and Death in Individuals with Hospital-Treated Alopecia Areata: A Registry-Based Cohort Study in Denmark

    May 2025 in “ Acta Dermato Venereologica ”
    Sissel Brandt Toft Sørensen, Prethibha George, Oladayo Jagun … Véra Ehrenstein
    Studysummary This study found that individuals with hospital-treated alopecia areata in Denmark had increased standardized incidence rates of serious infections, herpes zoster infections, lymphoma, cardiovascular events, and death compared to the age- and sex-matched general population.
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    Research cited in this study 16

    1. Alopecia Areata and Malignancies: Uncertainties Clarified by a Large-Scale Population-Based Study Archives of Dermatological Research · 2024
    2. Novel Investigational Drugs for Alopecia Areata and Future Perspectives Expert opinion on investigational drugs · 2024
    3. The Epidemiology of Hospital-Treated Alopecia Areata in Denmark, 1995–2016 Dermatology and therapy · 2024
    4. Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program American journal of clinical dermatology · 2024
    5. Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Meta-Analysis American Journal of Clinical Dermatology · 2023
    6. Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database Dermatology and therapy · 2023
    7. Safety of Janus Kinase Inhibitors in Patients with Alopecia Areata: A Systematic Review Clinical drug investigation · 2023
    8. Biomarkers in Alopecia Areata: A Systematic Review and Meta-Analysis Autoimmunity reviews · 2023
    9. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    10. Trends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population JAMA Dermatology · 2023
    11. The Burden of Alopecia Areata: A Scoping Review Focusing on Quality of Life, Mental Health, and Work Productivity Journal of the European Academy of Dermatology and Venereology · 2023
    12. Integrated Safety Analysis of Baricitinib in Adults With Severe Alopecia Areata From Two Randomized Clinical Trials British journal of dermatology/British journal of dermatology, Supplement · 2022
    13. Alopecia Areata: Current Understanding and Management Journal der Deutschen Dermatologischen Gesellschaft · 2022
    14. Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study Cancer Medicine · 2018
    15. Cardiovascular Risk in Patients with Alopecia Areata: A Propensity-Matched Retrospective Analysis Journal of the American Academy of Dermatology · 2016
    16. Alopecia Areata Increases the Risk of Stroke: A 3-Year Follow-Up Study Scientific Reports · 2015

    Related research 4

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013