Homeostasis, regeneration and tumour formation in the mammalian epidermis

    Daria Belokhvostova, Ieva Berzanskyte, Ana-Maria Cujba, Geraldine M. Jowett, Lucy Marshall, Johanna Prueller, Fiona M. Watt
    TLDR Stem cells in the skin help with healing and can also lead to cancer.
    This review discussed how technological advances like single cell transcriptomics and in vivo imaging enhanced understanding of the epidermis, particularly the stem cell compartment's nature and plasticity. It highlighted the roles of stem cells in maintaining homeostasis, aiding wound repair, and their involvement in cancer development. These insights underscored the complexity and adaptability of stem cells in the epidermis, contributing to both regenerative processes and tumor formation.
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