Hair Shaft Morphology, Elemental Composition, and Nanoparticles in Frontal Fibrosing Alopecia: A Case-Control Study

    January 2021 in “ Acta Dermato Venereologica ”
    Anna Lyakhovitsky, Elena Kartvelishvily, Theodoulos Drousiotis, Keren Lyakhovitsky, Seth J. Baum, Aviv Barzilai
    TLDR Titanium nanoparticles may trigger frontal fibrosing alopecia, so avoid products with them.
    This study investigated the potential link between titanium nanoparticles and frontal fibrosing alopecia (FFA) by analyzing hair morphology and elemental composition in 20 patients and 40 healthy controls. The findings showed that patients with FFA had significantly more cuticle weathering and a notable increase in particles containing titanium, chlorine, silicon, magnesium, and iron, with titanium-containing nanoparticles being 8.6 times more prevalent than in controls. These results suggested that titanium nanoparticles might be an environmental trigger for FFA, leading to the recommendation that patients avoid aggressive hair treatments and products containing titanium nanoparticles.
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