Hair Growth Promoting Effects of Limosilactobacillus Reuteri Isolated from Honeybee Through Wnt/β-Catenin Signal Transduction
April 2026
in “
Journal of the Korean Society of Cosmetology
”
Limosilactobacillus reuteri Wnt/β-catenin signaling pathway human follicle dermal papilla cells HFDPCs hair growth-related genes HGF IGF1 VEGF DKK1 hair follicle 5α-reductase hair follicle stem cells Wnt signaling pathway dermal papilla cells hair growth genes hepatocyte growth factor insulin-like growth factor 1 vascular endothelial growth factor dickkopf-related protein 1 hair follicles 5-alpha-reductase
Studysummary This study found that Limosilactobacillus reuteri NCHBL-005, derived from honeybees, may promote hair growth via a novel non-androgenic mechanism involving the Wnt/β-catenin signaling pathway, as it increased hair follicle size and number in mice and influenced related gene expression in human follicle cells.
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