Limosilactobacillus Fermentum MF10 Promotes Hair Growth Through Upregulation of Wnt/β-Catenin Signaling in C57BL/6 Mice

The study investigates the hair growth-promoting effects of Limosilactobacillus fermentum MF10 (MF10) in a mouse model. MF10 demonstrated anti-oxidative and anti-inflammatory properties in vitro and increased hair follicle size in vivo. It promoted hair growth by activating Wnt/β-catenin signaling and modulating VEGF levels. The treatment also influenced gut microbiota, specifically increasing Duncaniella abundance, which correlated with p-GSK3B protein expression. These findings suggest that MF10 could be a promising candidate for hair loss prevention, providing a basis for future clinical studies.