The Role of Glucagon-Like Peptide-1 Receptor Agonists in Hair Loss: Clinical Evidence and Proposed Mechanisms

    May 2026 in “ Dermatologic Surgery ”
    Nikkia Zarabian, Mina Farah, Amanda Stines, Adam Friedman
    Studysummary This study reports conflicting evidence on whether GLP-1 receptor agonists are associated with various forms of alopecia, suggesting dermatology practitioners should consider monitoring and counseling patients using these medications.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on journals.lww.com →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Increased Risk of Hair Loss with GLP-1 Receptor Agonists: A Real-World Multicenter TrinetX Cohort Study JAAD International · 2026
    2. Increased Risk of Telogen Effluvium with Tirzepatide Compared to Other Weight-Loss Medications: A Retrospective Cohort TriNetX Database Study Journal of the American Academy of Dermatology · 2025
    3. Association Between Androgenetic Alopecia and Glucagon-Like Peptide-1 Receptor Treatment in Type 2 Diabetes Mellitus Patients: A Retrospective Cohort Study International Journal of Dermatology · 2025
    4. Can Oral Minoxidil Be the Game Changer in Androgenetic Alopecia? A Comprehensive Review and Meta-Analysis Comparing Topical and Oral Minoxidil for Treating Androgenetic Alopecia Skin Health and Disease · 2025
    5. Alopecia and Semaglutide: Connecting the Dots for Patient Safety Journal of Cosmetic Dermatology · 2025
    6. Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review Skin Appendage Disorders · 2025
    7. Exploring the Hair Loss Risk in Glucagon-Like Peptide-1 Agonists: Emerging Concerns and Clinical Implications Journal of the European Academy of Dermatology and Venereology · 2025
    8. Glucagon-Like Peptide-1 Receptor Agonist Medications and Hair Loss: A Retrospective Cohort Study Journal of the American Academy of Dermatology · 2025
    9. Risk of Suicide, Hair Loss, and Aspiration with GLP1-Receptor Agonists and Other Diabetic Agents: A Real-World Pharmacovigilance Study Cardiovascular Drugs and Therapy · 2024
    10. Treatment of Insulin Resistance With Tirzepatide Leading to Improvement of Hair Loss JAAD Case Reports · 2024
    11. GLP-1 Agonists and Hair Loss: A Call for Further Investigation International Journal of Dermatology · 2024
    12. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss JAMA dermatology · 2022
    13. Interventions for Female Pattern Hair Loss JAMA Dermatology · 2017
    14. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012