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GlossaryGLP-1 receptor agonists

mimic a hormone to regulate blood sugar and promote fullness

GLP-1 receptor agonists are a class of medications that mimic the action of the glucagon-like peptide-1 (GLP-1) hormone, which helps regulate blood sugar levels by enhancing insulin secretion and inhibiting glucagon release. They are commonly used in the treatment of type 2 diabetes and can also promote weight loss by slowing gastric emptying and increasing feelings of fullness.

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research Risk of Alopecia Areata with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss

February 2025 in “medRxiv (Cold Spring Harbor Laboratory)”

GLP-1 agonists may increase the risk of hair loss.

Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database

research Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database

November 2024 in “Circulation”

GLP1-RAs may have higher reports of suicide and hair loss, but no strong evidence links them to these issues.

research Exploring the Hair Loss Risk in Glucagon-Like Peptide-1 Agonists: Emerging Concerns and Clinical Implications

January 2025 in “Journal of the European Academy of Dermatology and Venereology”

Newer GLP-1 drugs like semaglutide may cause hair loss.

research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects

59 citations, August 2021 in “Frontiers in Endocrinology”

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

research Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review

February 2025 in “Skin Appendage Disorders”

GLP-1 receptor agonists can cause skin reactions, facial fat loss, and hair loss, but may help with wound healing and skin conditions.

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community Gyno & testoterone level

in Finasteride 282 upvotes 9 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.