Use of Finasteride and Minoxidil for the Treatment of Androgenetic Alopecia: A Review

    Bruno Francelino Da Silva, Rafael Gomes Firmino, Sarah Rebeca Dantas Ferreira, Francisco Patrício de. Andrade Júnior
    TLDR Combining Minoxidil and finasteride is more effective for hair growth but may cause side effects.
    This review explores the effectiveness of Minoxidil and finasteride in treating androgenetic alopecia (AGA), noting that both drugs, available in topical and oral forms, effectively promote hair growth. Topical Minoxidil (2%-5%) can cause skin irritation and hypertrichosis, while oral Minoxidil (0.25-5.0 mg) improves adherence but poses cardiovascular risks. Topical finasteride (0.25-1.0%) is effective but may also lead to hypertrichosis and cardiovascular effects, with its oral form (1 mg/day) limited to men due to sexual and reproductive concerns. Combining Minoxidil and finasteride offers superior efficacy over monotherapy, suggesting that this approach could enhance clinical outcomes and patient adherence while minimizing side effects.
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