Enhancement of Percutaneous Absorption of Finasteride by Cosolvents, Cosurfactant, and Surfactants

    November 2009 in “ Pharmaceutical Development and Technology ”
    Yousef Javadzadeh, Javad Shokri, Somayeh Hallaj-Nezhadi … Ali Nokhodchi
    Studysummary This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.
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    Research cited in this study 12

    1. Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation Pharmaceutical Development and Technology · 2007
    2. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    3. Male Androgenetic Alopecia: Medical and Surgical Treatments The Journal of Men's Health & Gender · 2005
    4. Male Androgenetic Alopecia The Journal of Men's Health & Gender · 2004
    5. Ketoconazole as an Adjunct to Finasteride in the Treatment of Androgenetic Alopecia in Men Medical Hypotheses · 2003
    6. Fluridil, A Rationally Designed Topical Agent For Androgenetic Alopecia: First Clinical Experience Dermatologic Surgery · 2002
    7. Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily Journal of The American Academy of Dermatology · 2002
    8. Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2000
    9. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    10. Treatment of Hair Loss The New England Journal of Medicine · 1999
    11. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    12. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998

    Related research 1

    1. Study on Transdermal Permeation and Skin Accumulation of Finasteride Ethosomes Zhōnghuá yàoxué zázhì · 2004