Comparison Between Dutasteride and Finasteride in Hair Regrowth and Reversal of Miniaturization in Male and Female Androgenetic Alopecia: A Systematic Review

April 2024 in “ Dermatology reports ”

Almuntaserbellah Almudaimeegh, Hanadi AlMutairi, Fatimah AlTassan, Yomna Fozan Alquraishi, Khalid Nabil Nagshabandi

dutasteride finasteride androgenetic alopecia hair regrowth miniaturization randomized controlled trials prospective cohorts retrospective cohort studies placebo group adverse events Propecia

TLDR Dutasteride is more effective than finasteride for hair regrowth in male and female pattern hair loss, with similar side effects.

The systematic review, which encompassed nine studies (four randomized controlled trials, one single-arm trial, two prospective cohorts, and two retrospective cohort studies), compared the effectiveness of dutasteride and finasteride in treating androgenetic alopecia (AGA) in both males and females. Seven studies exclusively enrolled male participants, while only two included female participants. The results showed that all groups receiving various doses of dutasteride and finasteride exhibited a significant increase in hair count compared to the placebo group. Notably, dutasteride (0.5 mg) and dutasteride (2.5 mg) were significantly more effective than finasteride (1 mg) in increasing hair counts. Furthermore, no significant difference in adverse events was observed between finasteride and dutasteride. The conclusion is that dutasteride is more potent than finasteride in treating AGA in both males and females, and the adverse events between the two were comparable.

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