Cannabidiol in Skin Health: A Comprehensive Review of Topical Applications in Dermatology and Cosmetic Science

    August 2025 in “ Biomolecules ”
    Aura Rusu, Anca Daniela Fărcaș, Octavia-Laura Moldovan, Corneliu Tanase
    TLDR CBD may help with skin and hair issues, but more research is needed.
    The review highlights the potential of cannabidiol (CBD) in dermatology and cosmetic science, emphasizing its anti-inflammatory, antioxidant, and antimicrobial properties. CBD shows promise in managing skin conditions like acne, eczema, and psoriasis, and may also benefit hair health by promoting regrowth and addressing hair loss. Despite promising results, challenges such as poor water solubility and regulatory variability hinder its widespread use. The review underscores the need for more extensive clinical trials to fully understand CBD's mechanisms and optimize its formulations for topical applications. Advanced delivery systems are being developed to enhance CBD's efficacy, but further research is necessary to establish its safety and therapeutic potential in dermatology.
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