Androgenetic Alopecia

January 2017 in “ Elsevier eBooks ”

androgenetic alopecia male pattern baldness

Studysummary Androgenetic alopecia is a common form of hair loss in both men and women.

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Research cited in this study

19 / 19 results

research Follicular Density and Ratios in Scarring and Nonscarring Alopecia

19 citations , February 2013 in “The American Journal of Dermatopathology”

This study found that follicular density and various hair growth ratios differ statistically between nonscarring and scarring alopecia, though significant overlap exists due to factors like sample size and scalp variation.

research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla

122 citations , November 2010 in “Journal of Dermatological Science”

This study found that increased expression of type II 5α-reductase, androgen receptors, and Hic-5/ARA55 in dermal papilla cells upregulates androgen sensitivity, playing a key role in androgenetic alopecia pathogenesis.

research Hair Counts in Scalp Biopsy of Males and Females with Androgenetic Alopecia Compared with Normal Subjects

40 citations , June 2009 in “Journal of Cutaneous Pathology”

This study found that Iranian patients with androgenetic alopecia had a higher terminal to vellus hair ratio compared to previous studies in Whites, suggesting potential onset of miniaturization.

research Use of the TrichoScan to Assess Female Pattern Hair Loss

30 citations , April 2009 in “Dermatologic Surgery”

This study found that miniaturization of hair is present in some women with androgenetic alopecia, but diagnosis may also be based on differences in hair shaft diameter between scalp regions.

research Follicular Streamers (Stelae) in Scarring and Non-Scarring Alopecia

29 citations , July 2008 in “Journal of Cutaneous Pathology”

This study found that follicular streamers are mostly present in non-scarring alopecia cases, and tracking their location can improve diagnosis accuracy.

research Dermal Fibrosis in Male Pattern Hair Loss: A Suggestive Implication of Mast Cells

19 citations , February 2008 in “Archives of Dermatological Research”

This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.

research The Histopathology of Noncicatricial Alopecia

43 citations , March 2006 in “Seminars in Cutaneous Medicine and Surgery”

This review examines the histopathologic features of four common types of noncicatricial alopecia and reports no new clinical results.

research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia

44 citations , January 2006 in “Biological & Pharmaceutical Bulletin”

This research suggests that testosterone-induced expression of TGF-beta1 and type I procollagen may lead to perifollicular fibrosis in androgenetic alopecia, with finasteride inhibiting this process as a possible mechanism for its effects.

research Vertical vs. Transverse Sections in Alopecia Biopsy Diagnosis

33 citations , August 2005 in “The American Journal of Dermatopathology”

This article provides departmental contact information for Dr. Dirk M. Elston at the Geisinger Medical Center and reports no research findings.

research Evaluation and Treatment of Male and Female Pattern Hair Loss

203 citations , December 2004 in “Journal of The American Academy of Dermatology”

This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.

research Histological Features of Peripilar Signs Associated with Androgenetic Alopecia

95 citations , January 2004 in “Archives of Dermatological Research”

This study found that peripilar signs on the scalp are linked to perifollicular lymphocytic infiltrates in early androgenetic alopecia, detectable even in areas with high hair density.

research An Investigation of Apoptosis in Androgenetic Alopecia

19 citations , June 2002 in “American Journal of Dermatopathology”

This study found significant differences in bcl-2 expression between areas of the scalp affected and unaffected by androgenetic alopecia, suggesting a uniform follicle population or synchronized follicular cycling in affected areas.

Alopecia Areata But Not Androgenetic Alopecia Is Characterized By A Restricted And Oligoclonal T-Cell Receptor-Repertoire Among Infiltrating Lymphocytes

research Alopecia Areata But Not Androgenetic Alopecia Is Characterized By A Restricted And Oligoclonal T-Cell Receptor-Repertoire Among Infiltrating Lymphocytes

19 citations , March 1997 in “Journal of Cutaneous Pathology”

This study observed that patients with alopecia areata often have a T-cell receptor repertoire in skin lesions that suggests a specific antigen-driven immune response may be important in the disease's pathogenesis.

research DNA Determination of Human Hair Bulbs in Normal and Androgenetic Alopecia

1 citations , August 1994 in “Journal of Cutaneous Pathology”

This study found that matrix cells from normal hair follicles primarily had a 2C DNA content, while those in androgenetic alopecia showed a significant increase in cells with a higher DNA content.

research CD44 Expression in Alopecia Areata and Androgenetic Alopecia

5 citations , June 1994 in “Journal of Cutaneous Pathology”

In this study, CD44 expression was absent in alopecia areata-affected scalp, with some patients regaining expression after treatment despite no significant hair regrowth, suggesting involvement in the disease's pathogenesis.

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.

research The Transverse Anatomy of Androgenic Alopecia

42 citations , December 1990 in “The Journal of Dermatologic Surgery and Oncology”

This study found decreased hair density and altered follicular architecture in the balding frontal scalp of patients with androgenic alopecia, with increased vellus hairs noted.

research Alopecia

22 citations , June 1980 in “International Journal of Dermatology”

The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.

research Male Pattern Alopecia: A Histopathologic and Histochemical Study

94 citations , August 1975 in “Journal of Cutaneous Pathology”

In this study, the researchers observed that male pattern alopecia is characterized by miniature follicles, enlarged sebaceous glands, and an increased number of mast cells, without significant abnormalities in enzyme activity.