Alopecia in Children with Cancer: A Review from Pathophysiology to Management

    Caitlin A. Kearney, Conor Maguire, Vikash S. Oza, Christina S. Oh, Michael Occidental, Jerry Shapiro, Seth J. Orlow, Chana L. Glasser, Mario E. Lacouture, Nikita Lakdawala, Kristen I. Lo Sicco
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    TLDR Scalp cooling and minoxidil can help manage hair loss in children with cancer, but more research is needed.
    The review examines alopecia in children undergoing cancer treatment, focusing on its pathophysiology, management, and psychosocial impact. Scalp cooling is highlighted as a promising method to prevent chemotherapy-induced alopecia, supported by various studies for its efficacy and safety. The use of topical and oral minoxidil is also explored, showing potential benefits in managing hair loss. The review stresses the importance of addressing the psychological effects of alopecia in pediatric cancer patients and calls for further research to optimize treatment strategies.
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