Alopecia in Children with Cancer: A Review from Pathophysiology to Management

Low-dose oral minoxidil is safe for treating children's hair disorders.

Topical minoxidil and dietary supplements improved hair regrowth in children with hair loss from chemotherapy.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

Low-dose oral minoxidil combined with topical minoxidil improves hair growth in breast cancer patients with therapy-induced hair loss.

Low-dose oral and sublingual minoxidil seem safe for children with hair disorders.

The safety and tolerability of low-dose oral minoxidil for treating hair loss in adolescents is not clearly determined.

Low vitamin D levels are linked to various types of hair loss, but more research is needed before using it as a treatment.

Persistent radiation-induced hair loss is dose-dependent, and treatments like topical minoxidil can be effective.

Scalp cooling can help prevent hair loss from chemotherapy, but treatment should be tailored to the individual and more research is needed.

Scalp cooling is an effective way to prevent hair loss from chemotherapy.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Many people with alopecia experience high levels of social anxiety, anxiety, and depression, and while wigs can boost confidence, they may also cause anxiety.

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

Permanent hair loss after bone marrow transplant can be caused by chemotherapy or chronic graft-versus-host disease.

The document concludes that recognizing specific histological features of different nonscarring alopecias is crucial for accurate diagnosis and understanding hair loss progression.

Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.

Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Topical vitamin D3 does not prevent hair loss from chemotherapy.

A mushroom extract might reduce hair loss and liver damage caused by certain chemotherapy drugs in animals.

Minoxidil shortens baldness from chemotherapy by 50.2 days without significant side effects.

Minoxidil helps prevent hair loss from chemotherapy in rats.

Minoxidil not effective in preventing chemotherapy-induced hair loss.

Minoxidil speeds up hair growth in rats without prolonging growth phase.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.