Alopecia Areata and Tofacitinib: A Prospective Multicenter Study from a Saudi Population

    October 2021 in “ International Journal of Dermatology ”
    Alanoud Al-Marzoug, May AlOrainy, Lama Altawil … Ruaa Alharithy
    Studysummary This study found that tofacitinib effectively induced hair regrowth in 62.2% of severe alopecia areata patients in Saudi Arabia after six months, with higher baseline Severity of Alopecia Tool scores and past steroid use linked to reduced response.
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    Research cited in this study 19

    1. An Excellent Response to Tofacitinib in a Brazilian Adolescent Patient with Alopecia Areata: A Case Report and Review of the Literature Clinical Case Reports · 2019
    2. Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the European Academy of Dermatology and Venereology · 2019
    3. Evaluation of Association of Vitamin D in Alopecia Areata: A Case-Control Study of 100 Patients in a Tertiary Rural Hospital of Southern India Indian dermatology online journal · 2019
    4. Increased Prevalence of Vitamin D Deficiency in Patients with Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2018
    5. Vitamin D-Dependent Rickets Type II with Alopecia: A Rare Case Report DOAJ (DOAJ: Directory of Open Access Journals) · 2018
    6. Tofacitinib (Selective Janus Kinase Inhibitor 1 and 3): A Promising Therapy for the Treatment of Alopecia Areata: A Case Report of Six Patients International Journal of Trichology · 2018
    7. Objective Outcome Measures: Collecting Meaningful Data on Alopecia Areata Journal of The American Academy of Dermatology · 2017
    8. Review of Treatment for Alopecia Totalis and Alopecia Universalis International Journal of Dermatology · 2017
    9. Treatment of Alopecia Areata With Tofacitinib JAMA Dermatology · 2017
    10. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
    11. Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata JCI insight · 2016
    12. Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers Experimental Dermatology · 2016
    13. Combined Oral Pulse and Topical Corticosteroid Therapy for Severe Alopecia Areata in Children: A Long-Term Follow-Up Study Dermatologic therapy · 2015
    14. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015
    15. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    16. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014
    17. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014
    18. Association Between Interleukin 18 Polymorphisms and Alopecia Areata in Koreans Journal of Interferon & Cytokine Research · 2014
    19. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010

    Related research 9

    1. The Usefulness and Wellbeing of Tofacitinib in the Treatment of Alopecia Areata Journal of Armed Forces Medical College, Bangladesh · 2022
    2. Peripheral Neuropathy Associated with Tofacitinib Use in Alopecia Universalis Journal of Dermatology and Dermatologic Surgery · 2022
    3. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    4. Topical Tofacitinib in Treatment of Alopecia Areata Einstein (São Paulo) · 2020
    5. Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib PubMed · 2018
    6. Tofacitinib (Selective Janus Kinase Inhibitor 1 and 3): A Promising Therapy for the Treatment of Alopecia Areata: A Case Report of Six Patients International Journal of Trichology · 2018
    7. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
    8. Efficacy of Tofacitinib in Treatment of Alopecia Universalis in Two Patients Journal of the European Academy of Dermatology and Venereology · 2016
    9. The Experts Meetings on Psoriasis: Recommendations for Daily Practice Annales de dermatologie et de vénéréologie · 2011