Impact of Formulation Design and Lyophilisation on the Physicochemical Characteristics of Finasteride Nanosystems

February 2023 in “ Journal of Microencapsulation ”

Malik Muhammad Irfan, Shefaat Ullah Shah, Kifayat Ullah Shah, Nicolas Anton, Idoux-Gillet Ysia, Guillaume Conzatti, Kifayat Ullah Shah, Perennes Elise, Thierry Vandamme

finasteride nanosystem lyophilisation ultrasonication cryoprotectants chitosan trehalose androgenic alopecia topical delivery Propecia

Studysummary This study developed a stable lyophilized finasteride nanosystem for topical delivery and found that it was stable for 90 days and that formulations with 15% trehalose showed favorable characteristics for potential use in treating androgenic alopecia.

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