A Novel Nanogel Formulation of Finasteride for Topical Treatment of Androgenetic Alopecia: Design, Characterization and In Vitro Evaluation

July 2021 in “ International Journal of Applied Pharmaceutics ”

Divya Sanganabhatla, R Shyam Sunder

finasteride nanogel androgenetic alopecia topical treatment solubility permeability biocompatibility gelling capacity viscosity stability drug content spreadability cumulative drug release Propecia

TLDR The finasteride nanogel could be an effective topical treatment for hair loss.

The study developed and evaluated a novel finasteride (FSD) nanogel for topical treatment of androgenetic alopecia. The nanogel formulation aimed to enhance solubility, permeability, and biocompatibility, addressing issues with oral delivery. The optimized nanogel (C2 batch) demonstrated excellent gelling capacity, clear appearance, good viscosity, and stability. It showed a high drug content (91.25±0.9%), effective spreadability (6.7 cm/sec), and significant cumulative drug release (758.52±1.49 µg at 24 h). The results indicated that the finasteride nanogel could be a promising topical treatment for androgenetic alopecia.

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in Chat 78 upvotes 1 year ago

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community Is there a big difference between name brand and cheaper hair fibres?

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community How much difference hair fibers and mousse make

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The user applies Rogaine foam, Toppik hair fibers, and Tresemme mousse to improve hair appearance and has restarted finasteride after a year off. They are considering a hair transplant and are working on self-esteem related to hair loss.

community 7 months - 7 months oral dutasteride 0.5mg, 5 months oral minoxidil 12.5mg - 34 year old male

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community Getting Ed from 1mg of fin not sure what to do

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