BMI1 Is Required for Melanocyte Stem Cell Maintenance and Hair Pigmentation

    May 2023 in “ Pigment Cell & Melanoma Research ”
    Molly M. Wilson, Paul S. Danielian, Griffin Salus … Jacqueline A. Lees
    Studysummary In this study, researchers found that deleting the Bmi1 gene in murine melanocytes caused premature hair greying and loss of melanocyte lineage cells, highlighting BMI1's role in protecting melanocyte stem cells from stress and oxidative damage.
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    Research cited in this study 4

    1. Regulation of Melanocyte Stem Cell Behavior by the Niche Microenvironment Pigment Cell & Melanoma Research · 2018
    2. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    3. The Hair Cycle Journal of Cell Science · 2006
    4. Melanocyte Stem Cell Maintenance and Hair Graying Cell · 2005